Former American League MVP Jose Abreu makes his return to Chicago on Friday when the White Sox host the Houston Astros in the first game of a three-game series at Guaranteed Rate Field. Abreu, now 36, won the MVP award while playing for the White Sox in the COVID-shortened 2020 season. But after signing with the Astros in the offseason, he has struggled, hitting a career-worst .218 with zero home runs. On Friday, Houston is a -155 favorite (risk $155 to win $100) in the latest Astros vs. White Sox odds from Caesars Sportsbook, while Chicago is a +130 underdog. The over/under for runs scored is 8.5.
The game is one of 15 on the MLB schedule for Friday. Elsewhere in the majors, the rival Dodgers and Padres begin a key three-game series in Los Angeles, and the Rays and Yankees square off in the second game of a four-game series in the Bronx. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it is on a 17-12 on top-rated MLB picks to start the 2023 season. Anybody who has followed it has seen profitable returns.
For Wednesday, the model has locked in three confident MLB best bets. If you successfully parlay the picks, you’d be looking at a payout of more than 7-1. You can only see the model’s MLB picks at SportsLine.
Top MLB picks today
After simulating every game on Friday 10,000 times, the model is high on the Angels (+118) to beat the Guardians. The Angels’ Tyler Anderson, who is scheduled to start on Friday, has been solid in his last two starts, giving up just three earned runs and 10 hits over 11 2/3 innings. He is coming off a season-high 14 wins in 2022.
Anderson will face a Guardians lineup that has struggled mightily this season. Cleveland ranks last in the majors in home runs (19) and second to last in runs per game (3.41). The Guardians have lost seven of their last 11 games and are just 7-11 at home. In addition, the Guardians are 1-10 in their last 11 games against a left-handed starter.
Featured Game | Cleveland Guardians vs. Los Angeles Angels
How to make MLB parlays for May 12
The model also locked in two other best bets for Friday, including a play on an even bigger underdog. These picks can help you earn a huge payday if you combine them in a parlay. You can only see the model’s MLB parlay picks and best bets at SportsLine.
What MLB picks should you target for a payout of more than 7-1? And what underdog does the model like on Friday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 17-12 run on top-rated money-line picks, and find out.